| Flow visualization in a model of a bifurcated stent-graft. | |
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MedLine Citation:
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PMID: 16048375 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To use an in vitro flow model to investigate the flow patterns in a bifurcated stent-graft for abdominal aortic aneurysm (AAA) repair. METHODS: Experiments were performed in an in vitro test rig incorporating a simplified non-planar model of an AAA. A two-component bifurcated device consisting of a stent structure and transparent polyurethane "graft" was deployed in the AAA model. Using a blood analogue fluid, a pulsatile blood flow waveform simulating resting flow condition was produced by means of a piston pump system. Flow patterns in the lateral and anteroposterior planes of the stent-graft were recorded and analyzed using flow visualization techniques. RESULTS: The flow patterns within the stent-graft were complex and influenced by the geometry of the stent-graft itself, as well as that of the aortic neck and iliac vessels. Regions of flow separation, low velocity and stagnation, and slow oscillatory flow near the walls were seen in the main body of the stent-graft. Constriction at the stump in the contralateral limb resulted in flow disturbances and flow separation. Kinking at the junctions of stent segments and folding of the graft compounded these complex flow structures. CONCLUSIONS: The flow structures within stent-grafts are complex, with features that may predispose to thrombus formation. Arterial geometry, including aortic neck angulation and iliac vessel tortuosity, and the design of the stent-graft are factors that influence hemodynamics and may impact the performance of aortic stent-grafts. |
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Authors:
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Chuh K Chong; Thien V How; Peter L Harris |
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Publication Detail:
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Type: Comparative Study; In Vitro; Journal Article |
Journal Detail:
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Title: Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists Volume: 12 ISSN: 1526-6028 ISO Abbreviation: J. Endovasc. Ther. Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-07-28 Completed Date: 2005-11-15 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 100896915 Medline TA: J Endovasc Ther Country: United States |
Other Details:
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Languages: eng Pagination: 435-45 Citation Subset: IM |
Affiliation:
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School of Clinical Sciences, University of Liverpool, UK. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aortic Aneurysm, Abdominal
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surgery* Blood Flow Velocity Blood Vessel Prosthesis* Blood Vessel Prosthesis Implantation / methods* Graft Occlusion, Vascular / prevention & control Hemodynamics Models, Anatomic Prosthesis Design Sensitivity and Specificity Stents* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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