Document Detail

Flow velocity waveforms in uterine and umbilical arteries during the angiotensin II sensitivity test.
MedLine Citation:
PMID:  2187350     Owner:  NLM     Status:  MEDLINE    
The angiotensin II sensitivity test has been used to predict the development of hypertension during pregnancy. We investigated the systolic/diastolic ratios of flow velocity waveforms in the uterine and umbilical arteries by means of a color Doppler system in 15 healthy women at 24 to 26 weeks' gestation. A significant increase (p less than 0.001) was observed in the systolic/diastolic ratio in the uterine artery, which was unaffected by the location of the placenta. In five women a differential effect of angiotensin II on the systemic diastolic blood pressure and on the systolic/diastolic was observed: the uterine circulation appeared to have a slower response and a faster recovery than the diastolic blood pressure. No changes in the systolic/diastolic ratio in the umbilical artery were observed.
R U Erkkola; J P Pirhonen
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  162     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  1990 May 
Date Detail:
Created Date:  1990-06-15     Completed Date:  1990-06-15     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1193-7     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynecology, Turku University Hospital, Finland.
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MeSH Terms
Analysis of Variance
Angiotensin II / diagnostic use*
Arteries / physiology
Blood Flow Velocity / drug effects
Blood Pressure / drug effects*
Pregnancy / physiology*
Umbilical Arteries / physiology*
Uterus / blood supply*
Reg. No./Substance:
11128-99-7/Angiotensin II

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