Document Detail


Flow-sensitive 3D magnetic resonance imaging reveals complex blood flow alterations in aortic Dacron graft repair.
MedLine Citation:
PMID:  17670586     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
A thorough knowledge of both vascular anatomy and hemodynamics is of high interest for the understanding of the severity of the underlying disease, the therapeutic decision-making and follow-up. In this context, flow-sensitive 3D magnetic resonance imaging (MRI) offers the possibility to simultaneously acquire detailed information about vascular hemodynamics and morphology. Recent methodological progress, extensive validation of the technique and combination with advanced 3D blood flow visualization enables nowadays for a detailed depiction of normal and altered flow characteristics in large arteries such as the thoracic and abdominal aorta. We report the comprehensive MR analysis of hemodynamic alterations in an otherwise healthy patient who underwent a Dacron graft repair after traumatic rupture of the proximal descending aorta. Flow-sensitive time-resolved 3D MRI was employed to analyze the effects of the implantation of a Dacron prosthesis on local vascular hemodynamics. Despite the unsuspicious appearance on angiographic images, 3D blood flow visualization revealed the development of complex and substantially altered systolic blood flow within the graft. These initial findings might in future enrich vascular diagnostics, therapeutic decision making, graft design, or serve as a comprehensive research tool.
Authors:
Alex Frydrychowicz; Ernst Weigang; Mathias Langer; Michael Markl
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Publication Detail:
Type:  Journal Article     Date:  2006-05-18
Journal Detail:
Title:  Interactive cardiovascular and thoracic surgery     Volume:  5     ISSN:  1569-9285     ISO Abbreviation:  Interact Cardiovasc Thorac Surg     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2007-08-02     Completed Date:  2007-08-08     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101158399     Medline TA:  Interact Cardiovasc Thorac Surg     Country:  England    
Other Details:
Languages:  eng     Pagination:  340-2     Citation Subset:  -    
Affiliation:
Department of Diagnostic Radiology, University Hospital Freiburg, Albert-Ludwigs-University Freiburg, Hugstetter Str. 55, 79106 Freiburg, Germany. alex.frydrychowicz@uniklinik-freiburg.de
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