| Flow microfluorometric analysis of the cell cycle phase cytotoxicity of ARA-C. | |
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MedLine Citation:
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PMID: 7444164 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Mouse L1210 leukemia cells killed by ara-C, an anti-tumor agent widely used against leukemia, were demonstrated to be in the S phase of the cell cycle by flow microfluorometry. The point in S phase at which the L1210 cells died was shown to be dose dependent. At higher concentrations of ara-C cells died earlier in the S phase. |
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Authors:
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R A Hromas; D E Markel; V E Scholes |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Research communications in chemical pathology and pharmacology Volume: 30 ISSN: 0034-5164 ISO Abbreviation: Res. Commun. Chem. Pathol. Pharmacol. Publication Date: 1980 Nov |
Date Detail:
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Created Date: 1981-02-26 Completed Date: 1981-02-26 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0244734 Medline TA: Res Commun Chem Pathol Pharmacol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 365-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Cell Cycle / drug effects* Cell Survival / drug effects Cytarabine / pharmacology* DNA, Neoplasm / metabolism Fluorometry / methods Leukemia L1210 / metabolism Mice |
| Chemical | |
Reg. No./Substance:
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0/DNA, Neoplasm; 147-94-4/Cytarabine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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