Document Detail

Flow dynamics in internal thoracic artery grafts 10 years after coronary artery bypass grafting.
MedLine Citation:
PMID:  11833999     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Flow dynamics in internal thoracic artery grafts 10 years after surgery are not known. METHODS: Doppler examination was performed in native internal thoracic arteries as a control (n = 8) and in internal thoracic artery grafts to the left anterior descending coronary artery 6 months postoperatively (group A, n = 25), at 5 years (group B, n = 14), and at 10 years (group C, n = 11). RESULTS: Each graft group showed a diastolic to systolic peak velocity ratio of less than 1.0 at the proximal end, and more than 1.0 at the distal end, but the control group showed a ratio of less than 1.0 throughout the length of the artery. The diastolic peak velocity of the graft groups was significantly faster than that of the control group at the distal end (versus group A, p < 0.01; versus group B, p < 0.005; and versus group C, p < 0.05). The systolic peak velocity of the graft groups was significantly lower than that of the control at the proximal end (versus group A, p < 0.0001; versus group B, p < 0.005; and versus group C, p < 0.0005). There were no significant differences of flow velocities among the graft groups and graft diameter among the four groups. CONCLUSIONS: Although the internal thoracic artery is systolic predominant, when native artery is used as graft, it changes its hemodynamics to diastolic predominance, especially at the distal end. Even after 10 years, graft flow dynamics are unchanged. This hemodynamic character may be one of the factors related to the superior long-term patency.
Yukio Ichikawa; Hirokazu Kajiwara; Yasuharu Noishiki; Ichiya Yamazaki; Kenji Yamamoto; Takayuki Kosuge; Sunao Sato; Yoshinori Takanashi
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Annals of thoracic surgery     Volume:  73     ISSN:  0003-4975     ISO Abbreviation:  Ann. Thorac. Surg.     Publication Date:  2002 Jan 
Date Detail:
Created Date:  2002-02-08     Completed Date:  2002-02-22     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  15030100R     Medline TA:  Ann Thorac Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  131-7     Citation Subset:  AIM; IM    
First Department of Surgery, Yokohama City University School of Medicine, Yokohama, Japan.
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MeSH Terms
Angina Pectoris / physiopathology,  surgery
Aorta, Thoracic / physiology,  transplantation*
Blood Flow Velocity
Coronary Artery Bypass*
Echocardiography, Doppler
Postoperative Period
Vascular Patency / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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