| Flow conductivity of rat dermis is determined by hydration. | |
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MedLine Citation:
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PMID: 7548858 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The flow rate of phosphate buffered saline through dermis was measured as a function of applied pressure. Hyaluronan and collagen, the two principal materials which confirm resistance to flow in dermis, were not lost from the tissue during the experiments which lasted up to two days. From Darcy's Law, the average flow conductivities were 2 to 6 x 10(-12) cm4/dyn x s and decreased with increasing applied pressure. We conclude that the tissue is compacted in proportion to the applied pressure during the flow experiments. The hydraulic flow conductivity is described mathematically as a function of compaction induced by the applied pressure. |
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Authors:
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J L Bert; R K Reed |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Biorheology Volume: 32 ISSN: 0006-355X ISO Abbreviation: Biorheology Publication Date: 1995 Jan-Feb |
Date Detail:
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Created Date: 1995-11-01 Completed Date: 1995-11-01 Revised Date: 2008-11-21 |
Medline Journal Info:
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Nlm Unique ID: 0372526 Medline TA: Biorheology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 17-27 Citation Subset: IM |
Affiliation:
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Department of Chemical Engineering, University of British Columbia, Vancouver, Canada. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Body Water / physiology Collagen / physiology Hyaluronic Acid / physiology Pressure Rats Rats, Wistar Rheology Skin Absorption / physiology* Skin Physiological Phenomena* |
| Chemical | |
Reg. No./Substance:
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9004-61-9/Hyaluronic Acid; 9007-34-5/Collagen |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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