Document Detail


Flow-Directed Assembly of Block Copolymer Vesicles in the Lab-on-Chip.
MedLine Citation:
PMID:  23094655     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
We demonstrate a microfluidic approach to the production of block copolymer vesicles via flow-directed self-assembly in a segmented gas-liquid device. Chemical conditions that favor spherical micelles in the bulk are found to yield a nearly pure population of vesicles on-chip- a transformation of two full morphological steps- due to a coalescence mechanism enabled by high-shear. The production of polymeric vesicles via top-down control in a microfluidic device enables new processing routes to applications including drug delivery formulations in the lab-on-chip.
Authors:
Chih-Wei Wang; Aman Bains; David Sinton; Matthew G Moffitt
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-24
Journal Detail:
Title:  Langmuir : the ACS journal of surfaces and colloids     Volume:  -     ISSN:  1520-5827     ISO Abbreviation:  Langmuir     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-25     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9882736     Medline TA:  Langmuir     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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