Document Detail


Florida Red Tide Toxins (Brevetoxins) and Longitudinal Respiratory Effects in Asthmatics.
MedLine Citation:
PMID:  22053149     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Having demonstrated significant and persistent adverse changes in pulmonary function for asthmatics after 1 hour exposure to brevetoxins in Florida red tide (Karenia brevis bloom) aerosols, we assessed the possible longer term health effects in asthmatics from intermittent environmental exposure to brevetoxins over 7 years. 125 asthmatic subjects were assessed for their pulmonary function and reported symptoms before and after 1 hour of environmental exposure to Florida red tide aerosols for upto 11 studies over seven years. As a group, the asthmatics came to the studies with normal standardized percent predicted pulmonary function values. The 38 asthmatics who participated in only one exposure study were more reactive compared to the 36 asthmatics who participated in ≥4 exposure studies. The 36 asthmatics participating in ≥4 exposure studies demonstrated no significant change in their standardized percent predicted pre-exposure pulmonary function over the 7 years of the study. These results indicate that stable asthmatics living in areas with intermittent Florida red tides do not exhibit chronic respiratory effects from intermittent environmental exposure to aerosolized brevetoxins over a 7 year period.
Authors:
Judy A Bean; Lora E Fleming; Barbara Kirkpatrick; Lorraine C Backer; Kate Nierenberg; Andrew Reich; Yung Sung Cheng; Adam Wanner; Janet Benson; Jerome Naar; Richard Pierce; William M Abraham; Gary Kirkpatrick; Julie Hollenbeck; Julia Zaias; Eliana Mendes; Daniel G Baden
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Publication Detail:
Type:  JOURNAL ARTICLE    
Journal Detail:
Title:  Harmful algae     Volume:  10     ISSN:  1568-9883     ISO Abbreviation:  -     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-11-4     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101128968     Medline TA:  Harmful Algae     Country:  -    
Other Details:
Languages:  ENG     Pagination:  744-748     Citation Subset:  -    
Affiliation:
Children's Hospital Medical Center and University of Cincinnati, Cincinnati, Ohio, 45229.
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MeSH Terms
Descriptor/Qualifier:
Grant Support
ID/Acronym/Agency:
P01 ES010594-10//NIEHS NIH HHS; P50 ES012736-05S2//NIEHS NIH HHS

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