Document Detail

Flecainide-associated bradycardia-dependent torsade de pointes: another potential mechanism of proarrhythmia.
MedLine Citation:
PMID:  21029131     Owner:  NLM     Status:  In-Data-Review    
Although flecainide has a risk of proarrhythmia in patients with structural heart disease, its mechanism has been mainly ascribed to use-dependency and a rapid ventricular response to organized atrial tachyarrhythmias or to ventricular tachycardia. We present a patient who experienced recurrent syncope due to bradycardia-dependent torsade de pointes (TdP) associated with flecainide-related bradycardia and QT prolongation. Bradycardia-dependent TdP with QT prolongation can be considered as one of mechanisms of flecainide-induced proarrhythmia.
Han Sang Kim; Hui-Nam Pak; Jong Seoung Park; Sung Soon Kim
Publication Detail:
Type:  Journal Article     Date:  2010-10-28
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  36     ISSN:  1540-8159     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2013 Mar 
Date Detail:
Created Date:  2013-03-06     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  e84-6     Citation Subset:  IM    
Copyright Information:
©2010, The Authors. Journal compilation ©2010 Wiley Periodicals, Inc.
Yonsei University Health System, Seoul, Republic of Korea.
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