| Flaxseed supplementation in hyperlipidemic patients. | |
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MedLine Citation:
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PMID: 16607740 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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METHODS: 40 hyperlipidemic patients with plasma total cholesterol greater than 240 mg/dL were distributed in 3 groups: 10 patients who received hypo-lipidic diet (diet group), 10 patients who received hypo-lipidic diet plus statins (diet+HL group), 20 patients who received hypo-lipidic diet plus 20 g ground flax-seeds/day (diet+flax group). Body mass index (BMI), serum total cholesterol (TC), HDL-cholesterol (HDL-C), LDL-cholesterol (LDL-C), triglycerides (TG) and cholesterol/HDL-cholesterol ratio were measured at the beginning and after 60 days of treatment. RESULTS: Flaxseed supplementation was associated with significant reductions in TC (-17.2%), LDL-C (-3.9%), TG (-36.3%) and TC/HDL-C ratio (-33.5%). There were no significant differences in absolute change in BMI nor in percentage change in TC, HDL-C, LDL-C, TC/HDL-C ratio between flaxseed and statin groups. CONCLUSIONS: Dietary flaxseed significantly improves lipid profile in hyperlipidemic patients and may favorably modify cardiovascular risk factors. |
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Authors:
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Silvia Mandaşescu; Veronica Mocanu; Ana-Maria Dăscaliţa; Raluca Haliga; I Nestian; P A Stitt; Veronica Luca |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Revista medico-chirurgicală̆ a Societă̆ţ̜ii de Medici ş̧i Naturaliş̧ti din Iaş̧i Volume: 109 ISSN: 0048-7848 ISO Abbreviation: Rev Med Chir Soc Med Nat Iasi Publication Date: 2005 Jul-Sep |
Date Detail:
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Created Date: 2006-04-12 Completed Date: 2006-06-27 Revised Date: 2011-01-13 |
Medline Journal Info:
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Nlm Unique ID: 0413735 Medline TA: Rev Med Chir Soc Med Nat Iasi Country: Romania |
Other Details:
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Languages: eng Pagination: 502-6 Citation Subset: IM |
Affiliation:
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Roman City Hospital, Endocrinology/Diabetes Service, Gr.T. Popa University of Medicine and Pharmacy Iaşi, School of Medicine. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Atherosclerosis
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drug therapy,
prevention & control Body Mass Index Cholesterol, HDL / blood Cholesterol, LDL / blood Dietary Supplements* Flax* Humans Hypercholesterolemia / diet therapy Hyperlipidemias / blood, diet therapy* Lipid Metabolism* / drug effects Phytotherapy / methods* Seeds* Treatment Outcome Triglycerides / blood alpha-Linolenic Acid / therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Cholesterol, HDL; 0/Cholesterol, LDL; 0/Triglycerides; 463-40-1/alpha-Linolenic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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