Document Detail

Flat warts undergoing involution: histopathological findings.
MedLine Citation:
PMID:  900965     Owner:  NLM     Status:  MEDLINE    
Patients with multiple flat warts were observed during the period of involution, shortly before regression of the warts. The histopathological process was characterized by mononuclear cell infiltration around subpapillary blood vessels, exocytosis of mononuclear cells into the epidermis, and a spectrum of degenerative epidermal changes that culminated in focal areas of necrosis within the epidermis. Lesions near the end stage of involution did not show the histopathologic features of flat warts. The mononuclear cell-associated injury to the epidermis resembles that seen in delayed cutaneous hypersensitivity responses and suggests that regression of flat warts may be due to a cell-mediated rejection reaction.
A Berman; R K Winkelmann
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Archives of dermatology     Volume:  113     ISSN:  0003-987X     ISO Abbreviation:  Arch Dermatol     Publication Date:  1977 Sep 
Date Detail:
Created Date:  1977-10-20     Completed Date:  1977-10-20     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  0372433     Medline TA:  Arch Dermatol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1219-21     Citation Subset:  AIM; IM    
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MeSH Terms
Monocytes / pathology
Skin / pathology*
Warts / pathology*

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