Document Detail


Flash pulmonary edema.
MedLine Citation:
PMID:  19917337     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Flash pulmonary edema (FPE) is a general clinical term used to describe a particularly dramatic form of acute decompensated heart failure. Well-established risk factors for heart failure such as hypertension, coronary ischemia, valvular heart disease, and diastolic dysfunction are associated with acute decompensated heart failure as well as with FPE. However, endothelial dysfunction possibly secondary to an excessive activity of renin-angiotensin-aldosterone system, impaired nitric oxide synthesis, increased endothelin levels, and/or excessive circulating catecholamines may cause excessive pulmonary capillary permeability and facilitate FPE formation. Renal artery stenosis particularly when bilateral has been identified has a common cause of FPE. Lack of diurnal variation in blood pressure and a widened pulse pressure have been identified as risk factors for FPE. This review is an attempt to delineate clinical and pathophysiological mechanisms responsible for FPE and to distinguish pathophysiologic, clinical, and therapeutic aspects of FPE from those of acute decompensated heart failure.
Authors:
Stefano F Rimoldi; Melana Yuzefpolskaya; Yves Allemann; Franz Messerli
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Progress in cardiovascular diseases     Volume:  52     ISSN:  1532-8643     ISO Abbreviation:  Prog Cardiovasc Dis     Publication Date:    2009 Nov-Dec
Date Detail:
Created Date:  2009-11-17     Completed Date:  2010-01-07     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376442     Medline TA:  Prog Cardiovasc Dis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  249-59     Citation Subset:  AIM; IM    
Affiliation:
Swiss Cardiovascular Center Bern, University Hospital, Bern, Switzerland. stefano.rimoldi@insel.ch
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MeSH Terms
Descriptor/Qualifier:
Diagnosis, Differential
Heart Failure / diagnosis,  etiology,  physiopathology
Humans
Pulmonary Edema / diagnosis,  etiology*,  physiopathology*
Renin-Angiotensin System / physiology
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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