Document Detail

Fixed ratio combination of propranolol and bendrofluazide in the treatment of hypertension.
MedLine Citation:
PMID:  3886568     Owner:  NLM     Status:  MEDLINE    
The combination of beta adrenoceptor blocker, i.e. propranolol (80 mg) and a diuretic, i.e. bendrofluazide (2.5 mg) in a single capsule (Inderetic) produced an effective control of blood pressure in 12 out of 13 patients with mild and moderately severe hypertension in this single-blind study. Treatment for 12 weeks did not produce any changes in biochemical parameters and no change in ECG, except that a significant decrease in heart rate was observed. No serious side-effects were observed.
P Pandhi; B K Sharma; P L Sharma; P L Wahi
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Publication Detail:
Type:  Clinical Trial; Journal Article    
Journal Detail:
Title:  International journal of clinical pharmacology, therapy, and toxicology     Volume:  23     ISSN:  0174-4879     ISO Abbreviation:  Int J Clin Pharmacol Ther Toxicol     Publication Date:  1985 Feb 
Date Detail:
Created Date:  1985-05-28     Completed Date:  1985-05-28     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  8003415     Medline TA:  Int J Clin Pharmacol Ther Toxicol     Country:  GERMANY, WEST    
Other Details:
Languages:  eng     Pagination:  92-4     Citation Subset:  IM    
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MeSH Terms
Bendroflumethiazide / therapeutic use*
Blood Pressure / drug effects
Clinical Trials as Topic
Drug Combinations
Heart Rate / drug effects
Hypertension / drug therapy*
Middle Aged
Propranolol / therapeutic use*
Reg. No./Substance:
0/Drug Combinations; 525-66-6/Propranolol; 73-48-3/Bendroflumethiazide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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