| Fixed interval feeding does not entrain the circadian pacemaker in blind rats. | |
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MedLine Citation:
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PMID: 443404 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Male and female rats were blinded by orbital enucleation at 1 or 21 days of age and were housed along with intact controls in a temperature- and light-controlled room (22 +/- 2 degrees C, LD 12:12). At 40 days of age the rats were transferred to running wheel cages connected to an event recorder and their activity patterns were monitored for the next 11--16 wk. After 4--6 wk in the running wheels, the rats were subjected to a fixed interval feeding (FIF) schedule lasting 23 days followed by 4--6 wk of ad libitum feeding and watering. Of 19 blind rats with interpretable activity records, 14 showed no change in their activity patterns associated with the FIF other than the addition of a large component of activity before and after the feeding period every day. It was concluded that, in contrast to the squirrel monkey, FIF is not an important zeitgeber for blind rats. |
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Authors:
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F P Gibbs |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The American journal of physiology Volume: 236 ISSN: 0002-9513 ISO Abbreviation: Am. J. Physiol. Publication Date: 1979 May |
Date Detail:
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Created Date: 1979-07-25 Completed Date: 1979-07-25 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0370511 Medline TA: Am J Physiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: R249-53 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Age Factors Animals Blindness / physiopathology* Circadian Rhythm* Feeding Behavior / physiology* Female Male Motor Activity / physiology* Rats Time Factors |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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