Document Detail

Fixed breathing frequency decreases end-tidal PCO2 in humans.
MedLine Citation:
PMID:  1751474     Owner:  NLM     Status:  MEDLINE    
We tested the effect of a fixed breathing frequency on the partial pressure of CO2 in the end-tidal air (PETCO2) in resting healthy subjects. In the first experiment, three different rates of breathing were dictated: the same frequency of breathing as the subject's control one (1f), a double frequency (2f), and half of the control frequency (0.5f). 10 min dictate of 1f and 2f induced a decrease of PETCO2. The dictate of 0.5f had no significant effect on PETCO2. In the second experiment, 1f was dictated for 30 min, inducing a decrease of PETCO2 throughout the duration of the dictate. These results demonstrate that fixing the breathing frequency by the dictate affects the chemostatic control of ventilation.
M Vízek; V Smejkal; F Palecek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Physiological research / Academia Scientiarum Bohemoslovaca     Volume:  40     ISSN:  0862-8408     ISO Abbreviation:  Physiol Res     Publication Date:  1991  
Date Detail:
Created Date:  1992-01-30     Completed Date:  1992-01-30     Revised Date:  2008-04-02    
Medline Journal Info:
Nlm Unique ID:  9112413     Medline TA:  Physiol Res     Country:  CZECHOSLOVAKIA    
Other Details:
Languages:  eng     Pagination:  257-60     Citation Subset:  IM    
Institute of Pathophysiology, 2nd Medical Faculty, Charles University, Prague.
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MeSH Terms
Carbon Dioxide / metabolism*
Homeostasis / physiology
Hyperventilation / metabolism,  physiopathology
Middle Aged
Partial Pressure
Pulmonary Gas Exchange / physiology*
Respiration / physiology*
Time Factors
Reg. No./Substance:
124-38-9/Carbon Dioxide

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