Document Detail


Fixatives and methods of fixation in selected tissues of the laboratory rat.
MedLine Citation:
PMID:  679644     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The histologic appearances of tissues fixed by immersion and perfusion were compared, as well as the effects of these different fixatives: 10% neutral buffered formalin, Carnoy's fluid, and Bouin's fluid. Intravascular perfusion provided better tissue preservation than fixation by immersion. The quality of preservation by neutral buffered formalin was equal to that of Carnoy's fluid and Bouin's fluid, but the overall staining quality of the latter two was judged to be superior.
Authors:
W D Johnson; C M Lang; M T Johnson
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Clinical toxicology     Volume:  12     ISSN:  0009-9309     ISO Abbreviation:  Clin. Toxicol.     Publication Date:  1978  
Date Detail:
Created Date:  1978-10-18     Completed Date:  1978-10-18     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0205535     Medline TA:  Clin Toxicol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  583-600     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Brain / anatomy & histology
Fixatives*
Kidney / anatomy & histology
Liver / anatomy & histology
Lung / anatomy & histology
Perfusion
Rats / anatomy & histology*
Chemical
Reg. No./Substance:
0/Fixatives

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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