Document Detail

Five-year experience with midtrimester amniocentesis performed by a single group of obstetricians-gynecologists at a community hospital.
MedLine Citation:
PMID:  12066085     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: The purpose of this study was to determine the pregnancy loss rate after genetic amniocentesis that was performed by general obstetrician-gynecologists in a community hospital. STUDY DESIGN: Medical records and billing information were used to identify all genetic amniocenteses that had been performed by a group of general obstetricians-gynecologists from 1996 through 2000. Maternal charts were reviewed for data that were pertinent to the risk of fetal loss: maternal age, parity, ethnicity, procedure indication, gestational age at procedure, karyotype results, physician operator, gestational age at delivery, and live birth/stillbirth. RESULTS: During this 5-year time period, 370 procedures were performed by this physician group. Completed delivery outcomes were available on 369 of 370 patients (99.7%). Three patients underwent pregnancy termination. Data were analyzed on the remaining 366 patients. There was 1 pregnancy loss (amniocentesis at 17 weeks with vaginal bleeding at 21 week and preterm delivery at 24 weeks). There was 1 other procedure-related complication: membrane rupture 7 days after the procedure, with spontaneous resealing of the membranes after prolonged bedrest. CONCLUSION: Over a 5-year period, pregnancy loss after midtrimester amniocentesis performed by general obstetrician-gynecologists was 1 in 366 procedures.
Sean C Blackwell; Margot G Abundis; Paul C Nehra
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of obstetrics and gynecology     Volume:  186     ISSN:  0002-9378     ISO Abbreviation:  Am. J. Obstet. Gynecol.     Publication Date:  2002 Jun 
Date Detail:
Created Date:  2002-06-14     Completed Date:  2002-07-11     Revised Date:  2005-11-17    
Medline Journal Info:
Nlm Unique ID:  0370476     Medline TA:  Am J Obstet Gynecol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1130-2     Citation Subset:  AIM; IM    
Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Wayne State University, Detroit, MI, USA.
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MeSH Terms
Abortion, Spontaneous / etiology*
Amniocentesis / adverse effects*
Gynecology / methods*
Hospitals, Community*
Obstetric Labor, Premature / epidemiology,  etiology
Obstetrics / methods*
Pregnancy Trimester, Second*
Retrospective Studies
Comment In:
Am J Obstet Gynecol. 2002 Dec;187(6):1728   [PMID:  12501096 ]
Am J Obstet Gynecol. 2003 Feb;188(2):600; author reply 600-1   [PMID:  12592284 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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