| Five year clinical effect of coronary stenting and coronary artery bypass grafting in renal insufficient patients with multivessel coronary artery disease: insights from ARTS trial. | |
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MedLine Citation:
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PMID: 15860519 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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AIMS: To compare coronary stent implantation and bypass surgery for multivessel coronary disease in patients with renal insufficiency. METHODS AND RESULTS: In the ARTS trial, 142 moderate renal insufficient patients (Ccr<60 mL/min) with multivessel coronary disease were randomly assigned to stent implantation (n=69) or CABG (n=73). At 5 years, there was no significant difference between the two groups in terms of mortality (14.5% in the stent group vs. 12.3% in the CABG group, P=0.81), or combined endpoint of death, cerebrovascular accident (CVA), or myocardial infarction (MI) (30.4% in the stent group vs. 23.3% in the CABG group, P=0.35). Among patients who survived without CVA or MI, 18.8% in the stent group underwent a second revascularization procedure when compared with 8.2% in the surgery group (P=0.08). The event-free survival at 5 years was 50.7% in the stent group and 68.5% in the surgery group (P=0.04). CONCLUSION: At 5 years, the differences in mortality and combined incidence of death, CVA, and MI between coronary stenting and surgery did not reach statistically significant level. However, the occurrence of MACCE in the stent group was higher than in the CABG group, mainly driven by the higher incidence of repeat revascularization in the stent group. |
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Authors:
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Jiro Aoki; Andrew T L Ong; Angela Hoye; Lex A van Herwerden; J Eduardo Sousa; Adib Jatene; Johannes J R M Bonnier; Jacques P M A Schönberger; Nigel Buller; Robert Bonser; Wietze Lindeboom; Felix Unger; Patrick W Serruys |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Journal Article; Randomized Controlled Trial Date: 2005-04-28 |
Journal Detail:
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Title: European heart journal Volume: 26 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 2005 Aug |
Date Detail:
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Created Date: 2005-07-15 Completed Date: 2005-10-20 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: England |
Other Details:
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Languages: eng Pagination: 1488-93 Citation Subset: IM |
Affiliation:
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Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Coronary Artery Bypass / methods* Coronary Disease / surgery* Female Humans Kidney Failure, Chronic / complications* Male Middle Aged Myocardial Revascularization / methods Stents* Survival Analysis Treatment Outcome |
| Comments/Corrections | |
Comment In:
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Eur Heart J. 2005 Aug;26(15):1456-7
[PMID:
15917278
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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