Document Detail


Five novel prenylated xanthones from Resina Garciniae.
MedLine Citation:
PMID:  17994391     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Fourteen prenylated xanthone derivatives were isolated from gamboge, the dry latex of Garcinia hanburyi, and their structures were elucidated by a detailed spectroscopic analysis. Five of them, isogambogenic acid (1), desoxymorellinin (2), 10-methoxygambogenic acid (3), 10-methoxygambogic acid (4) and 10-ethoxy gambogic acid (5), are new compounds. All of them showed potent cytotoxicity against HL-60, SMMC-7721 and BGC-83 cells.
Authors:
Feng Feng; Wen-Yuan Liu; You-Sheng Chen; Qing-Long Guo; Qi-Dong You
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Journal of Asian natural products research     Volume:  9     ISSN:  1028-6020     ISO Abbreviation:  J Asian Nat Prod Res     Publication Date:    2007 Sep-Dec
Date Detail:
Created Date:  2007-11-12     Completed Date:  2008-05-14     Revised Date:  2009-07-21    
Medline Journal Info:
Nlm Unique ID:  100888334     Medline TA:  J Asian Nat Prod Res     Country:  England    
Other Details:
Languages:  eng     Pagination:  735-41     Citation Subset:  IM    
Affiliation:
Department of Phytochemistry, China Pharmaceutical University, Nanjing, China.
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MeSH Terms
Descriptor/Qualifier:
Drug Screening Assays, Antitumor
Garcinia / chemistry*
Molecular Structure
Spectrum Analysis / methods
Xanthones / chemistry,  isolation & purification*,  pharmacology
Chemical
Reg. No./Substance:
0/Xanthones

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