Document Detail


Fishing out a sensor for anti-inflammatory oils.
MedLine Citation:
PMID:  20813253     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Abstract/OtherAbstract:
The omega-3 fatty acids have anti-inflammatory and antidiabetic effects in humans. Now, Oh et al. (2010) demonstrate that the G protein-coupled receptor GPR120 is a receptor for omega-3 fatty acids on macrophages and fat cells. Activation of GPR120 by omega-3 fatty acids inhibits multiple inflammation cascades in macrophages and reverses insulin resistance in obese mice.
Authors:
Alan R Saltiel
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Publication Detail:
Type:  Comment; Journal Article    
Journal Detail:
Title:  Cell     Volume:  142     ISSN:  1097-4172     ISO Abbreviation:  Cell     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-09-03     Completed Date:  2010-09-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0413066     Medline TA:  Cell     Country:  United States    
Other Details:
Languages:  eng     Pagination:  672-4     Citation Subset:  -    
Copyright Information:
Copyright 2010 Elsevier Inc. All rights reserved.
Affiliation:
Life Sciences Institute, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, USA. saltiel@lsi.umich.edu
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Comment On:
Cell. 2010 Sep 3;142(5):687-98   [PMID:  20813258 ]

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