Document Detail

Fish Oil Supplementation And Physical Exercise Program: Distinct Effects On Different Memory Tasks.
MedLine Citation:
PMID:  23041182     Owner:  NLM     Status:  Publisher    
Both fish oil supplementation and physical exercise are able to induce benefits to mental health by providing an improvement in cognitive performance and enhancing neuroplasticity and protection against neurological lesions. The aim of the present study was to investigate the cognitive effects in rats of the: 1- a diary and prolonged fish oil supplementation (85mg/Kg/day) initiated from prenatal period to the midlife (300 day/old); 2- moderate physical exercise in treadmill initiated from adolescent period to midlife and 3- association of fish oil supplementation and moderate physical exercise protocol during the same period. Animals were submitted to the habituation in the open-field, object recognition and to the plus-maze discriminative avoidance tasks. Our results demonstrated that a diary and prolonged fish oil supplementation can facilitate the persistence of the long-term habituation and recognition memories without, however, affecting the discriminative avoidance memory. Conversely, although the program of physical exercise exerted no effects on habituation or objects recognition, it was able to potentiate the persistence of the discriminative avoidance memory. Such promnestic effects (induced by both fish oil supplementation and physical exercise) were not accompanied by alterations in emotionality or locomotor activity. Our findings suggest that fish oil supplementation, initiated from prenatal period to midlife, and physical exercise program applied throughout the life induced distinctly a better cognitive performance.
A L F Rachetti; R M Arida; C L Patti; K A Zanin; L Fernades-Santos; R Frussa-Filho; S Gomes da Silva; F A Scorza; R M Cysneiros
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-10-4
Journal Detail:
Title:  Behavioural brain research     Volume:  -     ISSN:  1872-7549     ISO Abbreviation:  Behav. Brain Res.     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-8     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8004872     Medline TA:  Behav Brain Res     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Copyright © 2012. Published by Elsevier B.V.
Departamento de Fisiologia, Universidade Federal de São Paulo, R. Botucatu, 862, Ed. Ciências Biomédicas, 5° andar, 04023900, São Paulo, SP, Brazil.
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