Document Detail


First trimester serum inhibin A in normal pregnant women.
MedLine Citation:
PMID:  17957376     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVES: To establish reference ranges for maternal serum inhibin A in normal first trimester pregnant women. MATERIALS AND METHODS: This was a cross-sectional study. We measured maternal serum inhibin A in normal pregnant women gestation age between 6(+0) and 14(+6) weeks using the enzyme-linked immunosorbent assay (ELISA) method. Maternal serum inhibin A was analyzed according to gestational ages (GA). RESULTS: Serum of 300 pregnancies was analyzed and the outcome demonstrated the median of maternal serum inhibin A according to gestational age. The levels of maternal serum inhibin A during the 6(0)-6(+6) week of gestations are lowest when compared with other gestational age. The levels of maternal serum inhibin A during 9(0)-9(+6) week of gestations are maximal. Maternal serum inhibin A then declined until 14 weeks of gestation. CONCLUSION: Serum inhibin A can be measured during the first trimester of pregnancy by using the recent ELISA technique. Our reference ranges might be useful for further studies, such as prediction of adverse pregnancy outcome in threatened abortion.
Authors:
Vorapong Phupong; Tharangrut Hanprasertpong; Sittisak Honsawek
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-10-24
Journal Detail:
Title:  Archives of gynecology and obstetrics     Volume:  277     ISSN:  0932-0067     ISO Abbreviation:  Arch. Gynecol. Obstet.     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-02-20     Completed Date:  2008-09-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8710213     Medline TA:  Arch Gynecol Obstet     Country:  Germany    
Other Details:
Languages:  eng     Pagination:  307-10     Citation Subset:  IM    
Affiliation:
Department of Obstetrics and Gynecology, Chulalongkorn University, Rama IV Road, Pathumwan, Bangkok, 10330, Thailand. vorapong.p@chula.ac.th
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MeSH Terms
Descriptor/Qualifier:
Cross-Sectional Studies
Enzyme-Linked Immunosorbent Assay*
Female
Gestational Age
Humans
Inhibins / blood
Pregnancy
Pregnancy Outcome
Pregnancy Trimester, First / blood*,  immunology
Prospective Studies
Reference Values
Reproducibility of Results
Thailand
Chemical
Reg. No./Substance:
0/inhibin A; 57285-09-3/Inhibins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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