Document Detail

First trimester placental volume and three dimensional power doppler ultrasonography in type I diabetic pregnancies.
MedLine Citation:
PMID:  22504827     Owner:  NLM     Status:  Publisher    
OBJECTIVE: This study aimed to investigate the placental volume and three dimensional (3D) power Doppler vascularization in type I diabetic pregnancies during the first trimester METHODS: 3D-power Doppler ultrasonography of the placenta was performed at 11 + 0-13 + 6 weeks in 32 pregnancies complicated by type I diabetes. Placental volume, vascularization index (VI), flow index (FI), and vascularization flow index (VFI) were calculated using a standardized setting. RESULTS: In nine pregnancies, a poor first trimester glycemic control was present as expressed by HbA1c levels ≥ 7%, whereas in the remaining 23 mothers, the HbA1c concentrations were <7%. No differences were found in the placental volumes of diabetic mothers when compared with reference limits. 3D Doppler placental vascular indices were significantly higher in diabetic mothers (VI delta value 0.99, p = 0.0012; FI delta value 0.64, p = 0.0008; VFI delta value 1.28, p = 0.0039) when compared with reference limits. Pregnancies with HbA1c ≥7% exhibited higher placental vascular indices when compared with diabetic mothers with better glycemic control. CONCLUSIONS: In type I diabetic mothers, placental vascular indices are increased and these modifications are more evident in pregnancies with poor first trimester glycemic control. © 2012 John Wiley & Sons, Ltd.
Giuseppe Rizzo; Alessandra Capponi; Maria Elena Pietrolucci; Eloisa Aiello; Domenico Arduini
Related Documents :
2748357 - Development of maternal-fetal attachment during pregnancy.
20032817 - Interaction of maternal peroxisome proliferator-activated receptor gamma2 pro12ala poly...
2717257 - Placental transfer and fetal effects of maternal sodium beta-hydroxybutyrate infusion i...
23073047 - Anti-rh(c), "little c," isoimmunization: the role of rhuepo in preventing late anemia.
19370357 - Complete mole coexistent with a twin fetus.
2925477 - Birth weight outcomes in a teenage pregnancy case management project.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-4-16
Journal Detail:
Title:  Prenatal diagnosis     Volume:  -     ISSN:  1097-0223     ISO Abbreviation:  -     Publication Date:  2012 Apr 
Date Detail:
Created Date:  2012-4-16     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106540     Medline TA:  Prenat Diagn     Country:  -    
Other Details:
Languages:  ENG     Pagination:  1-5     Citation Subset:  -    
Copyright Information:
© 2012 John Wiley & Sons, Ltd.
Fetal Medicine Center Genoma, Rome, Italy; Dept Obstetrics and Gynecology, Università di Roma 'Tor Vergata', Italy.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Cortical Thickness Parameters for Endoscopic Browlift Fixation.
Next Document:  Sustained telomere length in hepatocytes and cholangiocytes with increasing age in normal liver.