| First report of reproductive assistance in a woman affected by May-Hegglin anomaly. | |
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MedLine Citation:
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PMID: 22037684 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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PURPOSE: To report the first case of fertility treatment in a patient with May-Hegglin anomaly, a rare hematological disorder inherited as an autosomal dominant trait. METHOD: We present a case report of a 40-year-old nulliparous patient with May-Hegglin anomaly who underwent her first ICSI cycle with transfer of three fresh embryos. RESULTS: Prophylactic platelet transfusion obtained by single-donor apheresis was performed 1 h before the oocyte pick up. No complications were reported. No pregnancy was obtained. CONCLUSIONS: We report about the possibility to assist women affected by May-Hegglin anomaly requiring reproductive assistance. However, a multidisciplinary team composed of gynecologists and hematologists should follow such patients carefully, in order to carry out a complete clinical evaluation and to prevent the potential risks of bleeding. Clinicians must be vigilant in their presentation of risks, benefits, and alternatives. |
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Authors:
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Valeria Savasi; Arianna Laoreti; Massimiliano Elli; Tiziano Brambilla; Augusto Federici; Irene Cetin |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-10-30 |
Journal Detail:
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Title: Archives of gynecology and obstetrics Volume: - ISSN: 1432-0711 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-31 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8710213 Medline TA: Arch Gynecol Obstet Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Reproductive Medicine Centre, Unit of Obstetrics and Gynecology, Department of Clinical Sciences "L. Sacco", University of Milan, School of Medicine, Via GB Grassi 74, 20151, Milan, Italy, Valeria.Savasi@unimi.it. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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