| First-pass and steady-state magnetic resonance angiography of the thoracic vasculature using gadofosveset trisodium. | |
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MedLine Citation:
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PMID: 19787726 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To compare a high-resolution, ECG-gated, motion-compensated, steady-state magnetic resonance angiography (SS-MRA) of the thoracic vasculature to standard first-pass MRA (FP-MRA) using a blood-pool contrast agent (gadofosveset trisodium). MATERIALS AND METHODS: In all, 25 patients >or=18 years with congenital or acquired disease of the thoracic vasculature, who underwent both FP-MRA and SS-MRA, were retrospectively identified. Diameters of left superior pulmonary vein (LSPV), left pulmonary artery (LPA), and aortic arch (AA) were measured. Image quality for LSPV, LPA, AA, coronary ostia, and coronary sinus were assessed. Vessel sharpness of LPA and LSPV and contrast ratio (CR) of LSPV, LPA, and AA were calculated. RESULTS: SS-MRA yielded significantly higher image quality for all vessels, and significantly higher vessel sharpness for LSPV and LPA compared to the FP-MRA. SS-MRA revealed lower intra- and interobserver variability for vessel diameters compared with the FP-MRA. The FP-MRA showed higher CR compared to the SS-MRA. CONCLUSION: Motion-compensated high-resolution SS-MRA of the thoracic vasculature using gadofosveset trisodium offers superior image quality compared to standard FP-MRA. Although SS-MRA delivers no dynamic information it may prove specifically helpful as an add-on to FP-MRA for imaging of small vascular structures. |
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Authors:
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Claas P Naehle; Andreas M??ller; Winfried A Willinek; Carsten Meyer; Tobias Hestermann; Juergen Gieseke; Hans Schild; Daniel Thomas |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 30 ISSN: 1053-1807 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2009 Oct |
Date Detail:
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Created Date: 2009-10-05 Completed Date: 2009-12-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 809-16 Citation Subset: IM |
Copyright Information:
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(c) 2009 Wiley-Liss, Inc. |
Affiliation:
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Department of Radiology, University of Bonn, Germany. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Aged Aged, 80 and over Contrast Media / administration & dosage* Coronary Circulation* Female Gadolinium / administration & dosage* Humans Image Enhancement / methods Image Interpretation, Computer-Assisted / methods Magnetic Resonance Angiography / methods* Male Middle Aged Organometallic Compounds / administration & dosage* Retrospective Studies Thorax / blood supply* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Organometallic Compounds; 0/gadofosveset trisodium; 7440-54-2/Gadolinium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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