Document Detail


First-order alcohol elimination in severe alcohol intoxication in an adolescent: a case report.
MedLine Citation:
PMID:  19041554     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
We report a case of severe ethanol intoxications in a 14-year-old boy whose starting blood alcohol concentration was 490 mg/dL. The intoxication led to coma with hypoventilation, hypoxemia, hypothermia, and a life-threatening situation. Elimination of ethanol followed nonlinear first-order concentration-dependent pharmacokinetics. Fluid balance was disturbed because of marked diuresis, and respirator treatment was needed. The treatment of fluid balance and the risk of hypoxemia in severe alcohol poisoning are emphasized.
Authors:
Anne Lamminpää; Kalle Hoppu
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  The American journal of emergency medicine     Volume:  27     ISSN:  1532-8171     ISO Abbreviation:  Am J Emerg Med     Publication Date:  2009 Jan 
Date Detail:
Created Date:  2008-12-01     Completed Date:  2009-01-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8309942     Medline TA:  Am J Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  128.e5-6     Citation Subset:  IM    
Affiliation:
Division of Insurance, State Treasury, P.O. Box 10, FI-00054 Helsinki, Finland. anne.lamminpaa@fimnet.fi
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Alcohol-Induced Disorders / therapy*
Alcoholic Beverages / adverse effects
Alcoholic Intoxication / therapy*
Coma / etiology
Ethanol / adverse effects,  pharmacokinetics*
Humans
Male
Water-Electrolyte Imbalance / etiology,  therapy*
Chemical
Reg. No./Substance:
64-17-5/Ethanol

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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