| First myocardial infarction in smokers. | |
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MedLine Citation:
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PMID: 1889438 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 484 patients with a first myocardial infarction 155 were smokers at the time of infarction. Their unadjusted survival was superior to the non-smokers at 3 months follow-up, with a relative risk of 0.36 (95% confidence interval 0.22-0.59). Major baseline differences existed between the two populations. When these inequalities were taken into account through a multivariate Cox regression the relative risk was increased to 0.55 (95% confidence interval 0.33-0.93), but was still significantly lower than in non-smokers (P = 0.017). No difference in rate of reinfarction was observed between the two populations. The smokers tended to have a 'less serious infarction' than the non-smokers. However, adding variables that accounted for this into the Cox model did not cancel the impact of smoking. From the results it is suggested that the reduced mortality in smokers is due to a thrombus occurring at an earlier stage of the coronary artery disease. Thus, at the time of infarction smokers' left ventricular function tends to be less affected, and this is reflected in the improved survival rate among smokers in the first months after an acute myocardial infarction. |
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Authors:
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P Mølstad |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: European heart journal Volume: 12 ISSN: 0195-668X ISO Abbreviation: Eur. Heart J. Publication Date: 1991 Jul |
Date Detail:
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Created Date: 1991-10-17 Completed Date: 1991-10-17 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8006263 Medline TA: Eur Heart J Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 753-9 Citation Subset: IM |
Affiliation:
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Medical Department, Hamar Hospital, Norway. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Electrocardiography Female Follow-Up Studies Humans Male Middle Aged Myocardial Infarction / etiology, mortality*, pathology Norway / epidemiology Prognosis Proportional Hazards Models Recurrence Risk Factors Smoking / adverse effects* Survival Analysis Survival Rate |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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