| First identification of the neurotoxin homoanatoxin-a from mats of Hydrocoleum lyngbyaceum (marine cyanobacterium) possibly linked to giant clam poisoning in New Caledonia. | |
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MedLine Citation:
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PMID: 19895826 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report the first identification of homoanatoxin-a from benthic marine cyanobacteria (Hydrocoleum lyngbyaceum) samples collected in Lifou (Loyalty Islands, New Caledonia), where cases of giant clams (Tridacna maxima) intoxications were recorded during a severe ciguatera fish poisoning outbreak. Homoanatoxin-a was also detected in extracts of giant clams harvested in the surroundings of the contaminated area suggesting the possible link between these poisoning events and the occurrence of potentially neurotoxic Hydrocoleum. |
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Authors:
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Annick Méjean; Caroline Peyraud-Thomas; Anne Sophie Kerbrat; Stjepko Golubic; Serge Pauillac; Mireille Chinain; Dominique Laurent |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-11-04 |
Journal Detail:
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Title: Toxicon : official journal of the International Society on Toxinology Volume: 56 ISSN: 1879-3150 ISO Abbreviation: Toxicon Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-08-23 Completed Date: 2010-12-23 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 1307333 Medline TA: Toxicon Country: England |
Other Details:
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Languages: eng Pagination: 829-35 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Ltd. All rights reserved. |
Affiliation:
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Unité des Cyanobactéries (CNRS URA 2172), Institut Pasteur, Paris Cedex 15, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Bacterial Toxins / analysis*, chemistry Base Sequence Bicyclo Compounds, Heterocyclic / analysis*, chemistry Bivalvia / microbiology* Ciguatera Poisoning / epidemiology* Cyanobacteria / chemistry* Gas Chromatography-Mass Spectrometry Humans Marine Biology Molecular Sequence Data New Caledonia / epidemiology Polymerase Chain Reaction RNA, Transfer / genetics Sequence Homology, Nucleic Acid |
| Chemical | |
Reg. No./Substance:
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0/Bacterial Toxins; 0/Bicyclo Compounds, Heterocyclic; 0/homoanatoxin-a; 9014-25-9/RNA, Transfer |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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