Document Detail

First experience with endovascular ultrasound renal denervation for the treatment of resistant hypertension.
MedLine Citation:
PMID:  22580249     Owner:  NLM     Status:  In-Data-Review    
Aims: To evaluate a novel modality utilising ultrasound for renal denervation designed to reduce the duration of the intervention as well as to increase the consistency of the clinical outcome. Methods and results: Eleven consecutive patients suffering from resistant hypertension as defined by the ESH-ESC guidelines were treated by transcatheter renal denervation using the CE-marked PARADISE™ technology (ReCor Medical, Ronkonkoma, NY, USA). An average of 5.1 ultrasound emissions were delivered in each subject for a total denervation duration of less than four minutes and the treatment was well tolerated by all patients. Both office and home blood pressure measurements showed an immediate, significant and sustained decrease in blood pressure. Three-month results were comparable to published data on radiofrequency renal denervation with an average reduction in office and home blood pressure of -36/-17 mmHg and -22/-12 mmHg, respectively. Conclusions: Ultrasound renal denervation appears to be a safe and effective treatment for resistant hypertension and further studies will be performed to confirm these preliminary results.
Tom Mabin; Marc Sapoval; Vincent Cabane; Joanne Stemmett; Mano Iyer
Related Documents :
15446589 - Chronic hydrocephalus in adults.
7373319 - Effects of hypercapnia and arterial hypotension and hypertension on cerebrospinal fluid...
1029639 - Effect of moderate arterial hypotension combined with repeated withdrawal of cerebrospi...
20739769 - Normal pressure hydrocephalus after gamma knife radiosurgery for vestibular schwannoma.
24840789 - Breaking bad - the two sides of gut microbiota in portal hypertension.
3081349 - Cerebrospinal fluid pressure alterations in experimental communicating hydrocephalus. r...
12709659 - A tissue engineered heart valve implanted in a juvenile sheep model.
22699729 - An analysis of risk factors for arterial hypertension in adolescent students.
2320249 - Blood pressure and plasma catecholamines in never-treated parkinsonian patients: effect...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology     Volume:  8     ISSN:  1969-6213     ISO Abbreviation:  EuroIntervention     Publication Date:  2012 May 
Date Detail:
Created Date:  2012-05-14     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101251040     Medline TA:  EuroIntervention     Country:  France    
Other Details:
Languages:  eng     Pagination:  57-61     Citation Subset:  IM    
Mediclinic Vergelegen, Somerset West, South Africa.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  First-in-man experience with a new embolic deflection device in transcatheter aortic valve intervent...
Next Document:  Cerebrovascular accidents complicating transcatheter aortic valve implantation: frequency, timing an...