Document Detail

First experience with the Prismaflex HF 20 set in four infants.
MedLine Citation:
PMID:  21298618     Owner:  NLM     Status:  Publisher    
Purpose: Renal replacement therapy (RRT) in infants is challenging due to a lack of widely available technology that is specific to this patient population. We present our initial experience with the newly developed Prismaflex HF20® disposable set used on the Prismaflex® device in infants with renal failure. ?Patients: Four infants, age 5 to 24 months, were enrolled. Overall 120 treatment sessions were performed over 300 patient-days. Treatment monitoring included patient weight change and fluid balance, treatment efficacy, number of interventions, and alarms. ?Results: Desired fluid balance according to the prescribed weight loss was achieved in all patients (R²=0.86, p<0.0001). Treatment efficacy was monitored by blood urea nitrogen (BUN) and serum creatinine values at the start of RRT (59±17 mg/dL and 5.1±1.1 mg/dL) and their decrease after 4 hours of RRT (23±7 mg/dL and 2.2±0.6 mg/dL). Measured urea and creatinine clearances for the HF20 filter were 23±7 ml/min and 19±4 ml/min, respectively. No complications occurred. ?Conclusion: This is the first report on the use of the Prismaflex HF20 set in infants. No adverse events were observed, treatments were well tolerated in all patients, and flow rate adaptability to infants' needs was good.
Siegfried Rödl; Ingrid Marschitz; Christoph J Mache; Martin Koestenberger; Georg Madler; Thomas Rehak; Gerfried Zobel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-2-4
Journal Detail:
Title:  The International journal of artificial organs     Volume:  -     ISSN:  1724-6040     ISO Abbreviation:  -     Publication Date:  2011 Feb 
Date Detail:
Created Date:  2011-2-7     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7802649     Medline TA:  Int J Artif Organs     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Department of Pediatrics, Pediatric Intensive Care Unit, Medical University of Graz, Graz - Austria.
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