Document Detail

First day serum creatine kinase BB isoenzyme in high-risk infants.
MedLine Citation:
PMID:  2029919     Owner:  NLM     Status:  MEDLINE    
Serum creatine kinase BB (CK-BB) on the 1st day of life was measured by radioimmunoassay in 37 very low birth weight (VLBW) infants, 14 severely asphyxiated infants and 24 controls. The 31 survivors from the two high-risk groups were followed up for 12 months or more. VLBW non-survivors (n = 14) had significantly higher mean CK-BB levels than survivors (n = 23), (P less than 0.05). However, if only survivors were considered, CK-BB was a poor discriminator of outcome in either study group. First day serum CK-BB is not a useful predictor of neurodevelopmental outcome in surviving high-risk infants.
R A Primhak; E Simmonds
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  European journal of pediatrics     Volume:  150     ISSN:  0340-6199     ISO Abbreviation:  Eur. J. Pediatr.     Publication Date:  1991 Feb 
Date Detail:
Created Date:  1991-06-20     Completed Date:  1991-06-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7603873     Medline TA:  Eur J Pediatr     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  271-3     Citation Subset:  IM    
Department of Paediatrics, Children's Hospital, Western Bank, Sheffield, UK.
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MeSH Terms
Asphyxia Neonatorum / complications,  enzymology*
Brain Diseases, Metabolic / diagnosis*,  enzymology,  etiology
Creatine Kinase / blood*
Infant, Low Birth Weight / blood*
Infant, Newborn / blood
Reg. No./Substance:
0/Isoenzymes; EC Kinase

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