Document Detail

First case of post-conception Verteporfin exposure: pregnancy and neonatal outcome.
MedLine Citation:
PMID:  15453867     Owner:  NLM     Status:  MEDLINE    
PURPOSE: To assess pregnancy and neonatal outcomes in a woman accidentally exposed to Verteporfin photodynamic therapy in the third week of pregnancy. METHODS: Post-conception counselling and prospective follow-up by telephone interview at Telefono Rosso (Teratology Information Service) were carried out. The baby was examined at birth and at 26 months. RESULTS: The outcome of the pregnancy was normal and a healthy female child with a normal birthweight was born. The baby's follow-up was normal at 26 months. CONCLUSIONS: This is the first reported case of a childbearing woman being accidentally exposed to Verteporfin during pregnancy. No fetal or neonatal adverse effects were documented.
Marco De Santis; Brigida Carducci; Lidia De Santis; Angela Lucchese; Gianluca Straface
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta ophthalmologica Scandinavica     Volume:  82     ISSN:  1395-3907     ISO Abbreviation:  Acta Ophthalmol Scand     Publication Date:  2004 Oct 
Date Detail:
Created Date:  2004-09-29     Completed Date:  2004-12-09     Revised Date:  2008-03-17    
Medline Journal Info:
Nlm Unique ID:  9507578     Medline TA:  Acta Ophthalmol Scand     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  623-4     Citation Subset:  IM    
Telefono Rosso, Teratology Information Service, Department of Obstetrics and Gynaecology, Catholic University of the Sacred Heart, Rome, Italy.
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MeSH Terms
Choroidal Neovascularization / drug therapy*
Infant, Newborn
Photosensitizing Agents / therapeutic use*
Porphyrins / therapeutic use*
Pregnancy Outcome*
Reg. No./Substance:
0/Photosensitizing Agents; 0/Porphyrins; 129497-78-5/verteporfin

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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