Document Detail

On first looking into auriculo-ventricular asynchrony.
MedLine Citation:
PMID:  20180919     Owner:  NLM     Status:  MEDLINE    
Walter Gaskell's demonstration in 1882 that it was possible to block the passage of contraction from auricle to ventricle in the frog heart by means of a clamp spurred Joseph Erlanger (1906) to prevent, by similar means, impulse conduction through the bundle of (Wilhelm) His jun. (1893) in the mammalian heart. With a miniaturized polygraph to record the jugular and arterial pulsation, James Mackenzie (1902) displayed various grades of heart block in the human heart. His results were confirmed by Thomas Lewis using Willem Einthoven's (1903) ECG in 1911. But without instrumental help, Robert Spittal (1804-1852) recounted a case of reversible auriculo-ventricular block in 1830.
Caoimhghín S Breathnach; John B Moynihan
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Publication Detail:
Type:  Historical Article; Journal Article     Date:  2010-02-18
Journal Detail:
Title:  Pacing and clinical electrophysiology : PACE     Volume:  33     ISSN:  1540-8159     ISO Abbreviation:  Pacing Clin Electrophysiol     Publication Date:  2010 May 
Date Detail:
Created Date:  2010-06-15     Completed Date:  2010-09-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7803944     Medline TA:  Pacing Clin Electrophysiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  628-33     Citation Subset:  IM    
School of Medicine and Medical Science, University College Dublin, Dublin, Ireland.
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MeSH Terms
Atrioventricular Block / history*,  physiopathology
Cardiac Electrophysiology / history*
Heart Conduction System / physiopathology
History, 19th Century
History, 20th Century

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