Document Detail

Finite-element study of cerebrospinal fluid in mitigating closed head injuries.
MedLine Citation:
PMID:  22913097     Owner:  NLM     Status:  In-Process    
The mechanism of cerebrospinal fluid in mitigating closed head injuries caused by mild impacts was investigated by finite-element modeling. Three biomechanical models were constructed. In these models, cerebrospinal fluid was considered as a soft solid material, an inviscid fluid without intracranial pressure, and an inviscid fluid with normal intracranial pressure, respectively, while other conditions such as the finite-element mesh, the impact, and the boundary conditions were kept the same. The recently developed nearest nodes finite-element method was adopted to deal with large deformations in brain tissue. Results obtained from the numerical studies showed that cerebrospinal fluid was able to remarkably reduce the maximum peak strains, especially the shear strains induced by impacts and transmitted to the brain. Cerebrospinal fluid with intracranial pressure was able to further buffer relative oscillations between the skull and the brain.
Yunhua Luo; Zhaoxia Li; Hongxi Chen
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine     Volume:  226     ISSN:  0954-4119     ISO Abbreviation:  Proc Inst Mech Eng H     Publication Date:  2012 Jul 
Date Detail:
Created Date:  2012-08-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8908934     Medline TA:  Proc Inst Mech Eng H     Country:  England    
Other Details:
Languages:  eng     Pagination:  499-509     Citation Subset:  IM    
Department of Mechanical and Manufacturing Engineering, Faculty of Engineering, University of Manitoba, Winnipeg, Manitoba, Canada.
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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