Document Detail

Finite element predictions compared to experimental results for the effective modulus of bone tissue engineering scaffolds fabricated by selective laser sintering.
MedLine Citation:
PMID:  19199109     Owner:  NLM     Status:  MEDLINE    
A current challenge in bone tissue engineering is to create scaffolds with suitable mechanical properties, high porosity, full interconnectivity and suitable pore size. In this paper, polyamide and polycaprolactone scaffolds were fabricated using a solid free form technique known as selective laser sintering. These scaffolds had fully interconnected pores, minimized strut thickness, and a porosity of approximately 55%. Tensile and compression tests as well as finite element analysis were carried out on these scaffolds. It was found that the values predicted for the effective modulus by the FE model were much higher than the actual values obtained from experimental results. One possible explanation for this discrepancy, viz. the surface roughness of the scaffold and the presence of micropores in the scaffold struts, was investigated with a view to making recommendations on improving FE model configurations for accurate effective property predictions.
S Cahill; S Lohfeld; P E McHugh
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2009-02-08
Journal Detail:
Title:  Journal of materials science. Materials in medicine     Volume:  20     ISSN:  1573-4838     ISO Abbreviation:  J Mater Sci Mater Med     Publication Date:  2009 Jun 
Date Detail:
Created Date:  2009-05-07     Completed Date:  2009-07-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9013087     Medline TA:  J Mater Sci Mater Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1255-62     Citation Subset:  IM    
National Centre for Biomedical Engineering Science, National University of Ireland, Galway, Ireland.
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MeSH Terms
Biocompatible Materials / chemistry
Bone Substitutes / chemistry*
Bone and Bones / physiology*
Compressive Strength
Finite Element Analysis*
Materials Testing
Microscopy, Electron, Transmission
Nylons / chemistry
Polyesters / chemistry
Surface Properties
Tensile Strength
Tissue Engineering / methods*
Tissue Scaffolds*
Reg. No./Substance:
0/Biocompatible Materials; 0/Bone Substitutes; 0/Nylons; 0/Polyesters; 24980-41-4/polycaprolactone

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