Document Detail

Finite element modeling of the thoracic aorta: including aortic root motion to evaluate the risk of aortic dissection.
MedLine Citation:
PMID:  17852647     Owner:  NLM     Status:  MEDLINE    
OBJECTIVE: We propose that the aortic root motion plays an important role in aortic dissection. METHODS AND RESULTS: A finite element model of the aortic root, arch and branches of the arch was built to assess the influence of aortic root displacement and pressure on the aortic wall stress. The largest stress increase due to aortic root displacement was found at approximately 2 cm above the top of the aortic valve. There, the longitudinal stress increased by 50% to 0.32 MPa when 8.9 mm axial displacement was applied in addition to 120 mmHg luminal pressure. A similar result was observed when the pressure load was increased to 180 mmHg without axial displacement. CONCLUSIONS: Both aortic root displacement and hypertension significantly increase the longitudinal stress in the ascending aorta, which could play a decisive role in the development of various aortic pathologies, including aortic dissection.
C J Beller; M R Labrosse; M J Thubrikar; F Robicsek
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of medical engineering & technology     Volume:  32     ISSN:  0309-1902     ISO Abbreviation:  J Med Eng Technol     Publication Date:    2008 Mar-Apr
Date Detail:
Created Date:  2008-05-19     Completed Date:  2008-06-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7702125     Medline TA:  J Med Eng Technol     Country:  England    
Other Details:
Languages:  eng     Pagination:  167-70     Citation Subset:  IM    
Department of Cardiac Surgery, University Hospital Heidelberg, INF 326, 69120, Heidelberg, Germany.
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MeSH Terms
Aneurysm, Dissecting / physiopathology*
Aorta, Thoracic / physiopathology*
Aortic Aneurysm / physiopathology*
Blood Flow Velocity
Blood Pressure
Computer Simulation
Finite Element Analysis
Models, Cardiovascular*
Risk Assessment / methods*
Risk Factors
Shear Strength
Stress, Mechanical

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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