| Fine structure of 33 258 H-treated chromosomes. | |
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MedLine Citation:
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PMID: 964987 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Metaphase chromosomes of mouse strain L cells show strikingly uncondensed pericentric heterochromatic regions after treatment of living cells with the benzimidazol-derivative 33 258 Hoechst. In electron micrographs of total preparations after G-band staining the chromosomes are seen to be made up of irregularly folded fibrils of 200-400 A in diameter. In the uncondensed regions only very few fibrils laid loose loops are present, making it probable that only one fibril forms one chromatid. |
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Authors:
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H G Schwarzacher; A Gropp; F Ruzicka |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Human genetics Volume: 33 ISSN: 0340-6717 ISO Abbreviation: Hum. Genet. Publication Date: 1976 Aug |
Date Detail:
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Created Date: 1976-12-01 Completed Date: 1976-12-01 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 7613873 Medline TA: Hum Genet Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 259-62 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Benzimidazoles / pharmacology* Chromosomes / drug effects*, ultrastructure Fluorescent Dyes / pharmacology* Heterochromatin / metabolism L Cells (Cell Line) Mice |
| Chemical | |
Reg. No./Substance:
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0/Benzimidazoles; 0/Fluorescent Dyes; 0/Heterochromatin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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