Document Detail

Fine needle aspiration in aspergilloma of frontal sinus: a case report.
MedLine Citation:
PMID:  18702374     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: The increased incidence of fungal diseases in humans is most likely due to indiscriminate use of broad-spectrum antibiotics and increased numbers of immunocompromised patients. Although Aspergillus species are ubiquitous and normally nonpathogenic, they can be opportunistic pathogens in immunocompromised individuals. CASE: A 22-year-old immunocompetent man presented with a gradually increasing subcutaneous swelling near the root of his nose for previous 6 months. The mass was soft to firm, solid, nontender and immobile. There was no superficial skin ulceration and no local signs of inflammation. Proptosis of the left eye was present without any visual impairment. An osteolytic lesion that was contiguous with the subcutaneous mass, with the opacities of both the fontal sinuses was observed radiographically. Fine needle aspiration cytology (FNAC) demonstrated presence of branching hyphae in the cytoplasm of multinucleated giant cells along with mixed inflammatory cells. The species was identified by culture in Sabouraud's agar with chloramphenicol and wet mount with lactophenol cotton blue stain. CONCLUSION: Aspergillosis can remain dormant over a long period. Although uncommon, it can occur in immunocompetent patients. FNA is a very useful tool in establishing the diagnosis
Samira Kumar Behera; Manoj Patro; Debiprasad Mishra; Atanu Bal; Bodhisatwa Behera; Susanta Sahoo
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta cytologica     Volume:  52     ISSN:  0001-5547     ISO Abbreviation:  Acta Cytol.     Publication Date:    2008 Jul-Aug
Date Detail:
Created Date:  2008-08-15     Completed Date:  2008-08-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0370307     Medline TA:  Acta Cytol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  500-4     Citation Subset:  IM    
Department of Pathology, Maharaja Krushna Chandra Gajapati Medical College, Berhampur, Orissa, India.
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MeSH Terms
Aspergillosis / complications,  microbiology,  pathology*,  radiography
Aspergillus flavus / isolation & purification*
Biopsy, Fine-Needle
Bone Diseases, Infectious / microbiology,  pathology
Exophthalmos / microbiology,  pathology
Frontal Sinus / microbiology*,  pathology,  radiography
Frontal Sinusitis / microbiology*,  pathology,  radiography
Osteolysis / microbiology,  pathology

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