| Fine-needle aspiration cytology in a regional head and neck cancer center: comparison with a systematic review and meta-analysis. | |
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MedLine Citation:
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PMID: 18528906 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Fine-needle aspiration cytology (FNAC) is used to diagnose masses presenting in the head and neck region. No systematic review of FNAC in this group has yet been performed. METHODS: A systematic review of the published literature and meta-analysis of data extracted from the included studies were compared with a 10-year review of head and neck FNAC from our institution. RESULTS: Systematic review identified 30 studies; 3459 FNAC aspirates from all head and neck sites were included. Overall results were as follows: sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) were 89.6%, 96.5%, 93.1%, 96.2%, and 90.3%, respectively. Two thousand seven hundred two head and neck aspirates were included in our institutional review. Sensitivity, specificity, PPV, NPV, and accuracy were 89.5%, 98.5%, 97.3%, 94.0%, and 95.1%, respectively. CONCLUSION: Meta-analysis and comparative systematic review confirm that FNAC is highly effective in the diagnosis of head and neck masses, with some limitations. |
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Authors:
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Sankalap Tandon; Riad Shahab; James I Benton; Samit K Ghosh; Jonathan Sheard; Terry M Jones |
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Publication Detail:
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Type: Comparative Study; Journal Article; Meta-Analysis; Review |
Journal Detail:
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Title: Head & neck Volume: 30 ISSN: 1097-0347 ISO Abbreviation: Head Neck Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2008-08-22 Completed Date: 2008-11-14 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8902541 Medline TA: Head Neck Country: United States |
Other Details:
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Languages: eng Pagination: 1246-52 Citation Subset: IM |
Affiliation:
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Department of Otolaryngology-Head and Neck Surgery, Aintree University Hospitals NHS Foundation Trust, Lower Lane, Liverpool L97AL, United Kingdom. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biopsy, Fine-Needle
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methods* Combined Modality Therapy Female Head and Neck Neoplasms / mortality*, pathology*, therapy Humans Immunohistochemistry Male Neoplasm Invasiveness / pathology* Neoplasm Recurrence, Local / mortality, pathology* Neoplasm Staging Prognosis Risk Assessment Sensitivity and Specificity Survival Analysis |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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