Document Detail


Fine-needle aspiration cytology of ductal adenoma: report of a case associated with a mucocele-like lesion.
MedLine Citation:
PMID:  8575285     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Ductal adenoma (DA) is an uncommon breast lesion that can histologically and clinically mimic carcinoma. We performed a fine-needle aspiration (FNA) of a DA. Cytologically, the lesion had features overlapping with those of mucinous carcinoma (MC), mucocele-like lesion, lactating adenoma (LA), and in retrospect with intraductal papilloma (IP). The smears were highly cellular and contained numerous monolayered sheets of ductal cells with prominent punched-out, small vacuoles distending the cytoplasm. The nuclei were mostly round to oval and had bland chromatin. Occasionally cells with enlarged nuclei and conspicuous nucleoli were present. The background showed large mucin pools, scattered single cells with mild nuclear atypia, some with apocrine metaplasia, rare stripped nuclei, and a fibrovascular stromal component. Calcifications were also present. We compare our cytologic findings with those of the lesions considered in the differential diagnosis. Due to its rare incidence and unusual features. DA may represent a diagnostic pitfall on FNA. Increased awareness of its cytologic appearance may help prevent a misdiagnosis.
Authors:
C E Mesonero; S Tabbara
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Diagnostic cytopathology     Volume:  13     ISSN:  8755-1039     ISO Abbreviation:  Diagn. Cytopathol.     Publication Date:  1995 Oct 
Date Detail:
Created Date:  1996-03-12     Completed Date:  1996-03-12     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8506895     Medline TA:  Diagn Cytopathol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  252-6     Citation Subset:  IM    
Affiliation:
Department of Pathology and Laboratory Medicine, University of Rochester School of Medicine, NY, USA.
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MeSH Terms
Descriptor/Qualifier:
Biopsy, Needle
Breast Diseases / pathology*
Breast Neoplasms / pathology*
Diagnosis, Differential
Female
Humans
Middle Aged
Mucocele / pathology*
Papilloma, Intraductal / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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