Document Detail

Fine-needle aspiration cytology of Castleman disease: case report with review of the literature.
MedLine Citation:
PMID:  18855889     Owner:  NLM     Status:  MEDLINE    
Organs involved by Castleman disease (CD) may be investigated by fine-needle aspiration cytology. No specific cytomorphological criteria are currently described for a definitive diagnosis. The cytological features of three fine-needle aspirations from three different lymph nodes of a patient with histologically confirmed CD of the hyaline-vascular type are herein reported, with a review of the literature. The fine-needle aspirations showed branching capillaries associated with fragments of germinal center. Review of the literature yielded 12 other case reports with over half describing similar findings. Because branching hyalinized small blood vessels penetrating follicular germinal center are characteristic of CD of the hyaline-vascular type on histology, this finding in fine-needle aspirates should raise that diagnostic possibility.
Majorie Deschênes; René P Michel; Roger Tabah; Manon Auger
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  Diagnostic cytopathology     Volume:  36     ISSN:  1097-0339     ISO Abbreviation:  Diagn. Cytopathol.     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-11-12     Completed Date:  2009-08-12     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8506895     Medline TA:  Diagn Cytopathol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  904-8     Citation Subset:  IM    
Copyright Information:
(c) 2008 Wiley-Liss, Inc.
Department of Pathology, McGill University Health Center and McGill University, Montreal, QC, Canada.
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MeSH Terms
Biopsy, Fine-Needle
Germinal Center / pathology*
Giant Lymph Node Hyperplasia / diagnosis*,  pathology
Hyalin / cytology
Lymph Nodes / pathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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