| Fine-needle aspiration biopsy of the distal extremities: a study of 141 cases. | |
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MedLine Citation:
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PMID: 20093231 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We reviewed our cytopathology databases for an 11-year period to identify all fine-needle aspiration biopsy (FNAB) cases of palpable masses of the hand, wrist, ankle, or foot. Cases were included only if there was a subsequent tissue biopsy or a minimum 1-year clinical follow-up. Of 141 aspirates, 41, 23, 34, and 43 were from the hand, wrist, ankle, and foot, respectively. Specific benign or malignant diagnoses were achievable in 71.6% of cases, whereas the remaining cases were given a descriptive diagnosis (26.2%) or, infrequently, a "suspicious for" diagnosis (2.1%). Overall sensitivity and specificity for distinguishing a benign from malignant entity from all 4 sites were 100% and 96%, respectively, whereas positive and negative predictive values were 88% and 100%, respectively. The most common lesion was a ganglion. Of the benign neoplasms, giant cell tumor of tendon sheath (17) and desmoid-type fibromatosis (7) were most common. Of 31 malignancies, 24 were sarcomas: sarcoma not otherwise specified (6), high-grade pleomorphic sarcoma (5), and Ewing sarcoma (3) were most common. Seven nonsarcomas included melanoma (3), metastatic squamous carcinoma (2), and malignant lymphoma (2). An FNAB-procured cytopathologic diagnosis is clinically reliable in a high percentage of distal extremity mass lesions. |
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Authors:
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Joseph D Jakowski; Joel Mayerson; Paul E Wakely |
Publication Detail:
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Type: Evaluation Studies; Journal Article |
Journal Detail:
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Title: American journal of clinical pathology Volume: 133 ISSN: 1943-7722 ISO Abbreviation: Am. J. Clin. Pathol. Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-01-22 Completed Date: 2010-02-17 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0370470 Medline TA: Am J Clin Pathol Country: United States |
Other Details:
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Languages: eng Pagination: 224-31 Citation Subset: AIM; IM |
Affiliation:
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Department of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Ankle Biopsy, Fine-Needle* Extremities* Foot Ganglion Cysts / diagnosis Hand Humans Sarcoma / diagnosis Sensitivity and Specificity Soft Tissue Neoplasms / diagnosis* Wrist |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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