| Finasteride Adherence-Associated Factors in Chinese Benign Prostatic Hyperplasia Patients. | |
| | |
MedLine Citation:
|
PMID: 22179115 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Objectives: Medication noncompliance is a recognized problem worldwide. This study evaluated the factors associated with compliance, discontinuation and switching of finasteride among Chinese benign prostatic hyperplasia patients. Materials and Methods: A retrospective cohort study was conducted with 682 outpatients newly diagnosed with benign prostatic hyperplasia and prescribed with finasteride from January 2008 to December 2009, taken from a database. We evaluated their compliance by medication possession ratios, discontinuation and switching rate after the prescription for an average observation period of 15 months. Multiple association factors were identified and evaluated using multivariate logistic regression analyses. Results: The crude compliance level, discontinuation and switching rates were 29.3, 60.6 and 10.1%, respectively. Older age (≥60 years), combination therapy, medical insurance and chronic comorbidities were positively associated with good compliance. Younger age was significantly associated with drug discontinuation or switching. Those patients on finasteride monotherapy and without medical insurance were significantly associated with discontinuation of drugs. Conclusions: Patients <60 years of age, on monotherapy and without medical insurance were less likely to be compliant with their newly initiated finasteride treatment. Consequently, more efforts should be made among this group to increase treatment adherence. |
| | |
Authors:
|
Yun-Hua Lin; Yong-Guang Jiang; Jun-Sheng Wang; Yong Luo |
Related Documents
:
|
18038195 - Is diversity good? six possible conceptions of diversity and six possible answers. 2687475 - Dr. a.c. guyton: builder. 12716385 - Terms used to describe urinary tract infections--the importance of conceptual clarifica... 9575775 - Sustaining membership lecture award. dogma, the shade that blinds. 10495465 - Brevetoxin b4 isolated from greenshell mussels perna canaliculus, the major toxin invol... 16234875 - Psychotropic drug-induced neutropenia. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2011-12-15 |
Journal Detail:
|
Title: Urologia internationalis Volume: - ISSN: 1423-0399 ISO Abbreviation: - Publication Date: 2011 Dec |
Date Detail:
|
Created Date: 2011-12-19 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0417373 Medline TA: Urol Int Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
|
Copyright © 2011 S. Karger AG, Basel. |
Affiliation:
|
Beijing Anzhen Hospital, Capital Medical University, Beijing, China. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Synthesis of a [2.2]paracyclophane based planar chiral palladacycle by a highly selective kinetic re...
Next Document: Digestibility and ?-carotene release from lipid nanodispersions depend on dispersed phase crystallin...