Document Detail


Field testing of a fenbendazole treatment combined with hygienic and management measures against a natural Giardia infection in calves.
MedLine Citation:
PMID:  16959430     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The need of a combination of animal treatment and environmental measures against a natural Giardia infection in calves between the age of 1 and 6 months was emphasized and evaluated. Ten commercial farms with a total of 94 calves suffering from chronic diarrhea, ill thriving and impaired growth, were included in two subsequent studies. The first study indicated that treatment of all animals with fenbendazole at 15 mg/kg during 3 consecutive days combined with environmental measures on the final day of treatment, which were either removal of bedding, thorough cleaning and ammonia 10% disinfection or relocation of the treated animals to a Giardia free environment, resulted in a total reduction in cyst excretion for at least 2 weeks. In the second study, the immunofluorescence assay (Merifluor Cryptosporidium/Giardia; Meridian Diagnostics Inc., Cincinnati, Ohio) was used quantitatively and confirmed that the combination of treatment and environmental measures resulted in a total reduction of cyst excretion during 2 weeks and in a significant (P<0.05; >or=98.0%) reduction of the cyst excretion until at least 4 weeks after treatment. Furthermore, there was a noticeable improvement of the clinical symptoms in all animals towards day 28 after treatment and 4 months after treatment health in all calves was normal.
Authors:
Thomas Geurden; Jozef Vercruysse; Edwin Claerebout
Publication Detail:
Type:  Journal Article     Date:  2006-09-07
Journal Detail:
Title:  Veterinary parasitology     Volume:  142     ISSN:  0304-4017     ISO Abbreviation:  Vet. Parasitol.     Publication Date:  2006 Dec 
Date Detail:
Created Date:  2006-11-20     Completed Date:  2008-07-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7602745     Medline TA:  Vet Parasitol     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  367-71     Citation Subset:  IM    
Affiliation:
Laboratory of Parasitology, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B-9820 Merelbeke, Belgium. thomas.geurden@ugent.be
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MeSH Terms
Descriptor/Qualifier:
Animal Husbandry / methods
Animals
Antinematodal Agents / administration & dosage,  pharmacology*
Cattle
Cattle Diseases / drug therapy*,  prevention & control*
Disinfection / methods
Feces / parasitology
Fenbendazole / administration & dosage,  pharmacology*
Giardia / drug effects,  isolation & purification*
Giardiasis / drug therapy,  prevention & control,  veterinary*
Oocysts
Chemical
Reg. No./Substance:
0/Antinematodal Agents; 43210-67-9/Fenbendazole

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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