| Fibronectin plasma levels after cadaver kidney transplantation. | |
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MedLine Citation:
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PMID: 2981594 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The fibronectin plasma levels of 17 patients undergoing cadaver kidney transplantation were determined serially in the postoperative course using laser nephelometry. While 9 patients retained their grafts (group A), the grafts of 8 patients had to be removed (group B), mainly due to rejection, 3 patients had severe infections. In both groups a significant drop of the plasma fibronectin occurred after surgery. There were no significant differences between the two groups in the mean fibronectin levels. After the initial drop the group A patients exhibited rising values leading to a stable level. Progressively declining fibronectin plasma concentrations were found in 2 of 3 severely infected patients. Fluctuating values were found in 3 group B patients without a clear correlation to the rejection crises or the kidney function. The data suggest that the fibronectin plasma level does not seem to be a prognostic marker for graft rejection. But it might be useful in the important and often difficult differentiation between rejection and infection. |
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Authors:
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R Seitz; M Lutz; R Michalik; H Lange; H G Klingemann; R Egbring |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Blut Volume: 50 ISSN: 0006-5242 ISO Abbreviation: Blut Publication Date: 1985 Jan |
Date Detail:
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Created Date: 1985-03-08 Completed Date: 1985-03-08 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0173401 Medline TA: Blut Country: GERMANY, WEST |
Other Details:
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Languages: eng Pagination: 35-43 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Cadaver Creatinine / blood Cyclosporins / therapeutic use Cytomegalovirus Infections / etiology Female Fibronectins / blood* Graft Rejection Humans Immunosuppression / adverse effects Kidney Transplantation* Male Middle Aged Sepsis / etiology Shock, Hemorrhagic / etiology Staphylococcal Infections / etiology |
| Chemical | |
Reg. No./Substance:
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0/Cyclosporins; 0/Fibronectins; 60-27-5/Creatinine |
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