| Fibronectin, Cryoglobulinemia and Immune Complexes in Sjogren's Syndrome Patients. | |
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MedLine Citation:
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PMID: 12687039 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The problem of proper diagnosis, patient's status and disease progression is very actual for autoimmune diseases. Still the diagnosis of Sjogren's syndrome is more state of art than of science. Our preliminary investigations showed that serum fibronectin of elevated molecular weight may be probably considered as one of the diagnostic criteria in Sjogren's syndrome patients. The increase of molecular weight of FN chains from 220 kDa to 250 kDa derives from relative and absolute elevation in a content of N-acetylglucosamine in FN carbohydrate chains. The present results concern the presence of FN in cryoprecipitates and circulating immune complexes in Sjogren's syndrome patients and as it has been demonstrated this parameter may be used as a prognostic sign. |
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Authors:
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M. L. Anfimova; T. V. Lebedeva; N. V. Khodarev; V. I. Vassiliev; V. A. Nassonova |
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Publication Detail:
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Type: JOURNAL ARTICLE |
Journal Detail:
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Title: Russian journal of immunology : RJI : official journal of Russian Society of Immunology Volume: 1 ISSN: 1028-7221 ISO Abbreviation: Russ. J. Immunol. Publication Date: 1996 Dec |
Date Detail:
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Created Date: 2003-Apr-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9713940 Medline TA: Russ J Immunol Country: - |
Other Details:
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Languages: ENG Pagination: 29-34 Citation Subset: - |
Affiliation:
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Haematological Scientific Centre, RAMS, Moscow, Russia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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