| Fibromuscular dysplasia of the renal artery responsible for renovascular hypertension: a histological presentation based on a series of 102 patients. | |
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MedLine Citation:
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PMID: 15061042 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Fibromuscular dysplasia (FMD) is a rare non-atherosclerotic and non-inflammatory disease in the arterial system. The purpose of the study was a retrospective analysis of FMD in the renal artery. PATIENTS AND METHODS: A total number of 102 patients (mean age: 36.9 years) who suffered from renovascular hypertension underwent a surgical therapy. The operative specimens of the renal arteries were analysed with the lightmicroscop using histological and immunohistochemical methods. RESULTS: 101 patients (99.02%) presented a medial FMD (extensive-medial subtype in 56 patients, 54.9%, subadventitial subtype in 29 patients, 28.4% and combined subtype in 16 patients, 15.7%). In 1 patient (0.98%) an adventitial FMD was found. We observed the following complications: true and dissecting aneurysms (75 patients, 74.5%), arterio-venous fistulae (2 patients, 1.96%) and chronic thrombosis (10 patients, 9.8%). CONCLUSIONS: With the progress in angioplasty, not all patients suffering from FMD undergo a primary surgical therapy and therefore this lesion is less seen in the daily work of the histopathologist. |
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Authors:
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P N Vuong; P Desoutter; V Mickley; B Bültmann; K Rothenberger-Janzen; H Guyot; J Janzen |
Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: VASA. Zeitschrift für Gefässkrankheiten Volume: 33 ISSN: 0301-1526 ISO Abbreviation: VASA Publication Date: 2004 Feb |
Date Detail:
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Created Date: 2004-04-05 Completed Date: 2004-08-26 Revised Date: 2012-10-19 |
Medline Journal Info:
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Nlm Unique ID: 0317051 Medline TA: Vasa Country: Switzerland |
Other Details:
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Languages: eng Pagination: 13-8 Citation Subset: IM |
Affiliation:
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Unité d'Anatomie et de Cytologie Pathologiques, Hôpital Saint-Michel, Paris, France. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Desmin / analysis Female Fibromuscular Dysplasia / pathology*, surgery Humans Hypertension, Renal / pathology*, surgery Kidney Cortex / blood supply, pathology Middle Aged Muscle Cells / pathology Nephrectomy Renal Artery / pathology, surgery Renal Artery Obstruction / pathology*, surgery |
| Chemical | |
Reg. No./Substance:
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0/Desmin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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