Document Detail

Fibromuscular dysplasia of renal arteries: percutaneous revascularization based on hemodynamic assessment with a pressure measurement guidewire.
MedLine Citation:
PMID:  16475187     Owner:  NLM     Status:  MEDLINE    
Fibromuscular dysplasia (FMD) leading to renal artery stenosis and hypertension is one of the most common treatable causes of secondary hypertension. However, frequently it can be difficult to judge the anatomical severity of a stenotic lesion with various noninvasive and invasive imaging modalities. We present two patients with poorly controlled hypertension and FMD affecting the renal arteries, in whom there were no anatomically significant stenoses by renal magnetic resonance angiography or selective renal artery angiography. Utilizing a 0.014'' high fidelity micromanometer tipped PressureWire XT (Radi, Reading, MA), to measure intravascular pressure gradients throughout the diseased renal arteries, we identified physiologically significant stenoses, and successfully treated both patients with percutaneous transluminal angioplasty.
Ehtisham Mahmud; Michele Brocato; Vachaspathi Palakodeti; Sotirios Tsimikas
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions     Volume:  67     ISSN:  1522-1946     ISO Abbreviation:  Catheter Cardiovasc Interv     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-03-02     Completed Date:  2006-08-31     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100884139     Medline TA:  Catheter Cardiovasc Interv     Country:  United States    
Other Details:
Languages:  eng     Pagination:  434-7     Citation Subset:  IM    
Copyright Information:
Copyright (c) 2006 Wiley-Liss, Inc.
Division of Cardiovascular Medicine, San Diego School of Medicine, University of California, San Diego, California 92103-8784, USA.
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MeSH Terms
Angioplasty, Balloon / methods*
Arterial Occlusive Diseases / complications,  pathology,  therapy*
Fibromuscular Dysplasia / complications,  pathology,  therapy*
Hypertension, Renal / etiology
Magnetic Resonance Angiography
Renal Artery Obstruction / etiology,  pathology,  therapy*

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