Document Detail

Fibrocartilaginous embolic myelopathy in a lion (Panthera leo).
MedLine Citation:
PMID:  20597229     Owner:  NLM     Status:  MEDLINE    
A 6-yr-old, captive-born male lion (Panthera leo) with a 3-day history of acute and nonprogressive spastic paraplegia of the hind limbs and flaccid paraplegia of the left forelimb, was submitted for postmortem examination. Before and after the onset of the neurologic signs, neither hematologic nor other significant clinical abnormalities were observed. The only remarkable gross lesion was restricted to the C6-C7 segments of the spinal cord, where a focal and asymmetric enlargement of the cord displaced the nerve roots. On the cut surface, a poorly demarcated dark red hemorrhagic lesion involved the lateroventral funiculi and the ventral horn of the gray matter, exclusively on the left half of the cord. Extensive necrosis, hemorrhages, degeneration of the neuroparenchyma, and several fibrocartilaginous emboli occluding the lumina of intraparenchymal arteries were present within histologic sections of spinal cord. Emboli also were detected within the meningeal vessels. This is the first report of fibrocartilaginous embolic myelopathy occurring in a lion.
Emanuele Ricci; Paolo Cavicchio; Carlo Cantile
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians     Volume:  41     ISSN:  1042-7260     ISO Abbreviation:  J. Zoo Wildl. Med.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-05     Completed Date:  2010-08-24     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8915208     Medline TA:  J Zoo Wildl Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  334-7     Citation Subset:  IM    
Department of Animal Pathology, Faculty of Veterinary Medicine, University of Pisa, Viale delle Piagge, 2-56124 Pisa, Italy.
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MeSH Terms
Embolism / pathology,  veterinary*
Infarction / pathology,  veterinary*
Spinal Cord / pathology
Spinal Cord Diseases / pathology,  veterinary*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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