| Fibrinolytic therapy for very late stent thrombosis--is it a viable option? | |
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MedLine Citation:
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PMID: 20934665 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Stent thrombosis (ST) has a very high case fatality and morbidity rates. The risk of very late ST is significantly increased with drug-eluting stents (DES) compared to bare-metal stents for at least up to 4 years. Discontinuation of clopidogrel therapy is the single most important consistently identified risk factor. Immediate reperfusion, preferably by primary percutaneous coronary intervention (PCI), has been considered the therapy of choice. Compared to de novo ST-elevation myocardial infarction (STEMI), myocardial infarction (MI) related to ST has significantly higher major adverse cardiovascular events (MACE) and lower reperfusion rates. Due to the significantly higher mortality associated with STEMI due to ST, prompt revascularization assumes paramount significance. Our case reflects the potential utility of fibrinolytic therapy for STEMI due to very late ST. Systemic fibrinolysis should be considered for ST in the presence of ongoing significant ischemia and unavailability of prompt PCI. |
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Authors:
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Abdul Hakeem; Sabha Bhatti; Imran Arif; Mohamed Effat; Mehmet Cilingiroglu |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Cardiovascular revascularization medicine : including molecular interventions Volume: 11 ISSN: 1878-0938 ISO Abbreviation: Cardiovasc Revasc Med Publication Date: 2010 Oct-Dec |
Date Detail:
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Created Date: 2010-10-11 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101238551 Medline TA: Cardiovasc Revasc Med Country: United States |
Other Details:
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Languages: eng Pagination: 264.e13-5 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
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Division of Cardiovascular Diseases, College of Medicine, University of Cincinnati, Cincinnati, OH 45257-0542, USA. ahakeem@gmail.com |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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